To further validate the clinical association between Listerin and ABCA1 in human macrophages, we performed flow cytometric analysis of PBMCs isolated from control individuals and patients with ASCVD and found a marked upregulation of both Listerin and ABCA1 expression in CD11b+ monocyte subsets (Figure 5, D and E). The gene discussed is ITGAM; the disease is atherosclerosis.