ORM1 and glomerular disorder: Additionally, ORM1 may serve as an indicator of psoriatic inflammation.10 As an acute-phase protein, ORM1 can exert systemic effects influencing renal function, and its role in regulating inflammation and immune responses may indirectly affect the kidneys.11 Based on these findings, we hypothesize that ORM1 could be involved in podocyte injury and repair, particularly as inflammation contributes to podocyte damage in various glomerular diseases.