SOAT1 and Nephropathy: It is widely accepted that the JAK‐STAT signaling cascade plays a pivotal role in the regulation of diverse biological processes, notably in immune response and inflammation.[48] Recent studies have highlighted the role of the JAK‐STAT pathway in diabetic nephropathy, demonstrating its ability to trigger inflammation and oxidative stress, which in turn contributes to kidney damage.[49] Our spatial transcriptomic analyses showed an activated JAK‐STAT pathway in the Vehicle group.