EFT positively correlated with BMI in both groups; negatively related with BNP and positively with log leptin in HF group. In controls, EFT correlated with hsCRP (positive) and log ghrelin (negative). Leptin predicted EFT in HF but not after BMI adjustment; ghrelin and hsCRP remained significant in controls even after BMI adjustment. Here, NPPB is linked to hydrops fetalis.