The results have shown significantly elevated levels of GIP-10, Gal-3, and HIF-1 in vaccinated and non-vaccinated PF-associated COVID-19 patients compared to the control, but the vaccinated patients exhibited significantly (p<0.05) lower levels of GIP-10, Gal-3, and HIF-1 compared to non-vaccinated patients. This evidence concerns the gene LGALS3 and COVID-19.