Finally, GIP-10, Gal-3, and HIF-1 levels were increased significantly in non-vaccinated COVID-19 patients and vaccinated COVID-19 patients compared to controls, where also, the GIP-10, Gal-3, and HIF-1 levels of non-vaccinated patients were significantly (p<0.05) higher compared to vaccinated patients. This evidence concerns the gene CXCL10 and COVID-19.