SLC12A3 and Gitelman syndrome: Gitelman syndrome (GS) is a rare autosomal recessive disorder due to mutations in the SLC12A3 gene coding for a thiazide-sensitive sodium-chloride cotransporter (NCC) in the distal convoluted tubule [3,4]. This defect impairs the reabsorption of sodium and chloride, leading to compensatory activation of the renin-angiotensin-aldosterone system (RAAS) [3].