This included a Lyme disease panel, anti-nuclear antibody, erythrocyte sedimentation rate, C-reactive protein, herpes simplex antigen and PCR, varicella zoster IgG and IgM, SARS-CoV-2 IgG and IgM, heterophile antibody, thiamine, folic acid, Vitamin B12, and a complement panel. The gene discussed is CD40LG; the disease is herpes simplex infectious disease.