CEBPB and polycystic ovary syndrome: PCOS-IR and PCOS-NIR exhibit distinct DNA methylation profiles, suggesting different epigenetic mechanisms; 79 genes were differentially methylated between PCOS-IR and PCOS-NIR patients, and 40 genes were differentially methylated in PCOS vs. controls; CEBPB methylation was significantly different between PCOS-IR and PCOS-NIR, indicating a role in IR. Differentially methylated genes were linked to immune response, inflammation, and metabolic pathways.