PSEN1 and Parkinson disease: Through proteomic profiling of DZP for PD model, as well as prediction of potential targets for DZP constituents, we found that eight molecules were consistently present across both datasets: ATP7 A, CHRM1, GSK3B, GSTM1, PSEN1, PTPN1, SLC7 A11 and SOD2 (Fig. 6A, B).