Thus, the active ingredients of DZP, such as Daidzein, Ursolic acid, albiflorin, aeoniflorin, 3-HPPA, directly bind ATP7 A, GSK3B, SLC7 A11, SOD2, and inhibit neuronal ferroptosis in PD by significantly increasing the levels of GPX4 and SLC7 A11, reducing the levels of ACSL4 (Fig. 9). Here, ACSL4 is linked to Parkinson disease.