The Gas6/AXL pathway regulates angiogenesis, immune-related molecular markers, and the secretion of certain cytokines (MHC-I, PD-L1, IL-4, CCL3-5, and G-CSF) in the tumor microenvironment, and it also regulates the functions of various immune cells (NK, DC, M2, and Treg) [36]. Here, CD274 is linked to neoplasm.