FHIT and lung cancer: Song et al. revealed that Mycobacterium tuberculosis (Mtb) infection may potentiate lung cancer progression via FHIT loss of heterozygosity (LOH) [31], a finding subsequently corroborated by Brisebarre et al., who demonstrated that FHIT abrogation hyperactivates HER2 pathways, thereby driving tumor proliferation and metastatic dissemination [32].