BCR and chronic myelogenous leukemia, BCR-ABL1 positive: Other factors implicated in leukemogenesis include acquired or inherited genetic and epigenetic mutations, such as CLL (chromosome 13q deletion [del(13q)], hyperdiploidy) [41]; CML (9:22 translocation [Philadelphia chromosome] [q34; q11.2] or BCR‐ABL fusion); and AML (t(15;17), t(8;21), inv.