Secondary neoplasms in this subgroup encompassed a wide range of malignancies, such as colon adenocarcinoma, prostate adenocarcinoma, thyroid papillary carcinoma, invasive ductal breast carcinoma, endometrioid adenocarcinoma, mucinous adenocarcinoma, and CD30-positive lymphoproliferative disorders. This evidence concerns the gene TNFRSF8 and colon adenocarcinoma.