CD8A and infection: Their presence correlates with the efficacy of RAS vaccines, as their depletion impairs CD11c+ DC influx into the liver and hinders optimal CD8+ T-cell responses, reducing sterile immunity.342–344 In studies with a murine model, separating liver and blood stages of infection, it was revealed that liver stage-dependent activation of Vγ4+ γδ T cells was crucial for mouse survival.