TNF and rheumatoid arthritis: Swiss registry data revealed that first-line corticosteroid use was significantly higher among EORA patients, along with a lower follow-up rate for biological drug use.143 In a study by Genevay et al. involving 1 571 RA patients treated with anti-TNFα drugs, withdrawal rates and changes in Disease Activity Score (DAS28) were consistent across groups after two years.144 However, despite clinical improvements, EORA patients exhibited significantly less enhancement in HAQ scores.