Through GEPIA2 and TIMER2.0 database [17, 18], we also found that SIRPα expression was negatively correlated with CD8+ T cells infiltration, and SIRPα overexpression in HCC was correlated with poor prognosis of patients (Fig. 1J and Fig. S1B, C). The gene discussed is SIRPA; the disease is hepatocellular carcinoma.