Consistent with this, a study on patients with colorectal cancer (n = 24) with stages II and III found that supplementation with 500 mg DHA and 118 mg EPA daily for 8 wk reduced the concentration of serum TNF-⍺ compared with placebo (corn oil) ( −0.61 ± 0.68 compared with −0.08 ± 0.65 pg/mL, P = 0.01) [32]. The gene discussed is TNF; the disease is colorectal cancer.