SCRIB and neoplasm: For example, three conserved cell polarity genes – scribble (scrib), lethal giant larvae [lgl; also known as l(2)gl] and discs-large (dlg; also known as dlg1) – are collectively named as neoplastic tumor suppressor genes (Bilder, 2004; Bilder and Perrimon, 2000; Bilder et al., 2000; Gateff, 1978).