There was a tolerogenic shift in the transcriptional profile of CD11b+ cells, with Il1b and Il6 transcripts more highly expressed in Kaede-green cells, and genes associated with an immunosuppressive state, including Il10, Tgfb1, and Mrc1 higher in Kaede-red cells resident in the tumour for 24 to 72 hours. The gene discussed is MRC1; the disease is neoplasm.