These changes were confirmed in CT26 tumours, but the dynamics and output of mdTAM differentiation differed from MC38 tumours, with 30% of Kaede-green CD11b+Ly6C+ cells showing MHC-II expression by 24 hours, and ultimately ∼65% of Kaede-red mdTAMs were MHC-II+ (Supplementary Fig S4G). The gene discussed is ITGAM; the disease is neoplasm.