Furthermore, in Ova-IC–stimulated tumours, we observed increased intracellular TNFα in Ly6C+MHC-II+ mdTAMs that had bound or internalised Ova-IC compared to Ova-647-stimulated cells (Fig 4K), but this increase was not present in Ly6C+MHC-II– mdTAMs (Fig 4L). The gene discussed is TNF; the disease is neoplasm.