PPARG and neoplasm: When comparing newly infiltrating Kaede-green cells present in the tumour for 24h with those present for 72h, we observed a change in expression of two transcription factors (TFs) critical for macrophage state, with down-regulation of Cebpb and upregulation of Pparg (Supplementary Fig S1I); the latter is associated with polarisation towards anti-inflammatory macrophages or tissue residency (37,38).