On average during periods of infection, Presepsin was 41% lower (51,462–30,188 pg/mL) (P = 0.001) and procalcitonin was 51% lower (0.77–0.38 ng/mL) (P < 0.001) while there was no difference in sTrem-1 or CRP compared to non-infected periods. The gene discussed is CRP; the disease is infection.