Additionally, transforming growth factor‐β2 (TGFβ2) derived from NG2 glia regulated CX3CR1‐modulated immune response via its receptor TGFBR2 in microglia, highlighting the significant roles of the communication between NG2 glia and microglia in maintaining brain immune homeostasis in PD [28]. This evidence concerns the gene CX3CR1 and Parkinson disease.