Immunofluorescent microscopy detected a clear co‐localization of CMTM6 with EGFR and RAB11, whereas the co‐localization of CMTM6 and EGFR with EEA1, RAB7, or LAMP1 was not evident (Figure 2E), suggesting that CMTM6 is co‐localized with EGFR mainly in recycling endosomes, preventing EGFR from lysosome‐mediated degradation in NSCLC cells. This evidence concerns the gene RAB11A and non-small cell lung carcinoma.