In contrast, CMTM6, a transmembrane protein, is emerging as a key player in immune evasion in cancers like breast cancer and melanoma, promoting us to focus our research on CMTM6.[14] The presence of CMTM6 in the EGFR interactome was confirmed by immunoblotting of the column‐bound proteins (Figure 1B). Here, CMTM6 is linked to melanoma.