CMTM6 and non-small cell lung carcinoma: To further investigate the direct interaction between EGFR and CMTM6, glutathione S‐transferase (GST) pull‐down assays were performed with bacterially expressed GST or GST‐fused CMTM6 and in vitro transcribed/translated EGFR variants (wild‐type and the NSCLC clinically relevant L858R, T790M, and L858R/T790M mutants).[24] Immunoblotting with the EGFR antibody showed that CMTM6 was capable of interacting with wild‐type as well as the mutated EGFR (Figure 1E).