STAT3 and cancer: Furthermore, inhibitionof the STAT3 signaling pathway was confirmed by Western blot analysis.These findings are consistent with our data (Figures  and ). Vimentin, an intermediate filament protein thatsupports the epithelial–mesenchymal transition (EMT), contributesto metastasis by enhancing the invasive capability of cancer cells.Our findings indicate that niclosamide suppresses the levels of EMT-relatedproteins Vimentin and ZEB1.