CALCA and periodontitis: Levels of growth factors (G-CSF), inflammatory cytokines (IFN-γ, IL-1α, IL-6, IL-12p70, IL-13, and TNF-α), and chemokines (KC, MCP-1, MIP-1α, MIP-1β, and RANTES) in BM extracellular fluid and serum, which were elevated after 28 d of LIP exposure, returned to baseline following resolution of periodontitis (Figure 7A).