Netea et al. reported that CD4+CD25+ Treg numbers and IL-10 levels were significantly reduced in TLR2 KO mice, but not in TLR4 KO mice, compared to WT littermate controls, and that monocyte recruitment to the site of infection and IFN-γ levels were increased in TLR2 KO mice following infection with Candida albicans54. The gene discussed is CD4; the disease is infection.