The sEPSC frequency for PON-PH cells was significantly higher than that for STR-PH cells (Figure 3L), the sEPSC amplitude for PON-PH cells was significantly larger than that for STR-PH cells (Figure 3M), the sEPSC rise time for PON-PH cells was significantly longer than that for MD-PH and STR-PH cells (Figure 3N), the sEPSC decay time for PON-PH cells was significantly longer than that for MD-PH cells (Figure 3O), and the sEPSC half width for PON-PH cells was significantly wider than that for MD-PH cells (Figure 3P). Here, PON1 is linked to Menkes disease.