Representative flow cytometric graphs of Tfh (CD4+CXCR5+ICOS+), Treg (CD4+CD25hiCD127low) and Tfr (CD4+CXCR5+CD25hiCD127low) cells in SLE-nA, SLE-A and HC groups are shown in Figure 5A. Here, ICOS is linked to systemic lupus erythematosus.