KLHL17 and Intellectual disability: Kelch-like family member 17 (KLHL17) is predominantly expressed in the brain and plays a crucial role in neuronal development and function, deletions and/or mutations in KLHL17 have been linked to neurodevelopmental disorders in humans, e.g., intellectual disability, autism spectrum disorder, and infantile spasms, but the etiology and pathogenesis remain largely enigmatic.1