Based on previously identified factors (gender, age, smoking status, drinking status, hypertension, diabetes, CVD history, CRP, SII, LDL-c, eGFR) that influence all-cause mortality prognosis, as well as commonly debated risk factors for adverse CKD prognosis (education levels, marriage status, FPIR, lipid-lowering drugs history), we defined this as the traditional factors model. This evidence concerns the gene CRP and diabetes mellitus.