*MPO-ANCA and PR3-ANCA according to the 2017 consensus. LoA - level of agreement (%). Scores: 1 - strongly disagree, 2 - disagree, 3 - undecided, 4 - agree, 5 - strongly agree. Reproduced with permissions from Moiseev et al. (9). AIH-1 - autoimmune hepatitis type 1. PBC - primary biliary cholangitis. PSC - primary sclerosing cholangitis. CD - Crohn’s disease. UC - ulcerative colitis. ASCA - anti-Saccharomyces cerevisiae antibodies. ANCA - antineutrophil cytoplasmic antibodies. P-ANCA - perinuclear antineutrophil cytoplasmic antibodies. This evidence concerns the gene MPO and sclerosing cholangitis.