MALAT1 and myocardial infarction: Shyu et al. (2020) further confirmed this by showing that hyperbaric oxygen induced the expression of lncRNA MALAT1, which suppresses the expression of exosomal miR-92a in a rat model of myocardial infarction, thus promoting angiogenesis and improving the infarcted area. Additionally, Ishii et al. (2006) and others identified a susceptibility locus for myocardial infarction (MI) on chromosome 22q12.1 through a large-scale case-control association study using single nucleotide polymorphisms (SNPs).