Another study performed by Nicholas et al.33 reported that the IL-33/ST2 axis mediates the development of EoE in mice elicited by percutaneous sensitization, and deficiency of IL-33 receptor ST2 significantly inhibits the process of EoE by a decrease in eosinophilic numbers accumulated in the esophagus of ST2−/−(deficient) mice. Here, IL33 is linked to eosinophilic esophagitis.