Consistently, the significant upregulation of HSD3B7 was observed in 92% (46 of 50) of the paracancerous tissues from HCC patients, which was associated with downregulation of miR-122 (r = −0.2958, p = 0.0242) (Figures 8E and S8). The gene discussed is HSD3B7; the disease is hepatocellular carcinoma.