HSD3B7 and neoplasm: Strikingly, overexpression of HSD3B7 in hepatocytes rescued the miR122-reduced liver tumor burden, showed by significantly elevated tumor incidence (Figure 6D, miR-122 vs. miR-122+HSD3B7: 0% vs. 100%) and induced tumor number and size (Figure 6E, bar2 vs. bar3).