Additionally, the mutation of the tumor suppressor gene APC will activate the Wnt signaling pathway, which is believed to be the initial event of CRC, in which APC’s 1039th codon 5bp base deletion exists in somatic cell mosaic phenomenon, speculated as one of the reasons for the early onset of CRC (onset age <50 years) (Gong, 2015). This evidence concerns the gene APC and colorectal carcinoma.