HGF exerts its biological functions by triggering a cascade of downstream signaling pathways through its receptor, c-MET, which plays a significant role in various types of cancers (Brown, 2016; Hofbauer et al., 2010; Giannoni et al., 2011; Cascone et al., 2017; Ogunwobi et al., 2013; Ono et al., 2006). Here, HGF is linked to cancer.