To verify whether this phenomenon also occurs in PCOS, we transfected si-Nrf2 and si-PINK1 into DHEA- and FFA-induced model cells after metformin treatment and compared the results to those of the Model+Metformin group to evaluate mitophagy, oxidative stress, lipid deposition levels, and other factors. Here, PINK1 is linked to polycystic ovary syndrome.