PPIB and posterior cortical atrophy: To determine whether C/EBP-β plays a crucial role in PTE-induced apoptosis in awakening PCa cells, we established stable C/EBP-β knockdown DU145 and LNCaP cell lines using lentiviral transfection of shC/EBP-β plasmids, with a nonsense plasmid (scramble) used as a control.