CB-8F4CAR-iNK T cells had significantly elevated ICOS expression relative to AD-8F4CAR-iNK T cells, with distinct ICOS-enriched populations identified in clusters 5, 11, and 7 by UMAP dimensionality reduction, suggesting enhanced anti-tumor potential of the CB-CAR-iNK T cells (Figures 3F, G) (26, 27). This evidence concerns the gene ICOS and neoplasm.