Interestingly, CB-8F4CAR-iNK T cells exhibited superior cytolysis against PR1/HLA-A2+ U937 cells and primary AML patient samples compared to AD-8F4CAR-iNK T cells, while CB-8F4CAR-iNK T cells retained the ability to lyse CD1d+ cell lines at a similar level compared to AD-8F4CAR-iNK T cells (Figures 4A, B). This evidence concerns the gene CD1D and acute myeloid leukemia.