Univariate analysis revealed that T stage (p = 0.002), lymphatic metastasis (p = 0.007), tumor stage (p = 0.005), CD8+ T cell density in the tumor (p = 0.001), B cell density in the tumor (p = 0.001), TIM-1+B cell density in the tumor (p = 0.001), and TIM-1+B cell density in the TDLN (p = 0.003) were significantly associated with OS in LUAD patients. The gene discussed is HAVCR1; the disease is neoplasm.