CD4 and neoplasm: Additionally, there was no significant relationship between TIM-1+B cells in the TDLN and the density of CD4+ T cells (p = 0.4258, r = 0.0712, 95% CI −0.1102 to 0.2479) or CD8+ T cells (p = 0.1094, r = −0.1433, 95% CI −0.3152 to 0.0376) in the tumor (Supplementary Figures S3E, F).