In the tumor primary lesion, patients with lower density of TIM-1+B cells had longer OS (mOS, 84 vs. 54 months; p < 0.0001, HR = 2.574, 95% CI 1.356 to 4.889) (Figure 4B) and DFS (mDFS, 53.0 vs. 23.1 months; p = 0.018, HR = 1.721, 95% CI 1.035 to 2.862) (Figure 4C). Here, HAVCR1 is linked to neoplasm.