Higher NEU levels were identified as an independent risk factor for Budd-Chiari syndrome recurrence (P = 0.003, OR = 1.197), while higher levels of ALB (P = 0.033, OR = 0.967) and AFP (P = 0.025, OR = 0.92) were found to have protective effects against Budd-Chiari syndrome recurrence.Among the various endovascular interventions for Budd-Chiari syndrome, patients undergoing stent implantation seemed to have a lower risk of recurrence compared to those undergoing simple balloon dilation (P = 0.021, OR = 0.419). Here, AFP is linked to hepatic veno-occlusive disease.