TP53 and breast carcinoma: Given the ability of BTHP to trigger apoptosis in breast cancer cells,24 we aimed to explore whether the apoptotic effect of BTHP is associated with its ability to target p53 protein.93 Toward this, we conducted a molecular docking study toward p53 protein (PDB id: 1TUP) and assessed the binding affinity score of BTHP.