The relationships between Se intake and the presence of a T2DM diagnosis, fasting blood glucose (FBG), fasting insulin, and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), were assessed using multivariate linear and logistic regression analyses, adjusting for age, sex, education, income, body mass index, physical activity, smoking, medication use, and family history of T2DM. This evidence concerns the gene INS and Insulin resistance.