On the other hand, a viable study of inflammation is the measure of inflammasomes and proinflammatory cytokines such as IL, especially IL-1β, which has been linked to neuroinflammation. To predict if there is a relationship between peripheral inflammasomes and dementia, levels of protein in peripheral blood mononuclear cells (PBMCs) were studied. Studies on Gasdermin D (GSDMD) have followed since it was previously linked to pyroptosis and the release of IL-1β. The gene discussed is IL1B; the disease is dementia.