The Root Mean Square Deviation (RMSD) analysis of Pixuvri in complex with key cervical cancer-related proteins—BubR1 (PDB ID: 2WVI), Cell Division Cycle Protein 20 Homolog (PDB ID: 4N14), MAD2 (PDB ID: 2VFX), and TPX2 (PDB ID: 3KND)—offers valuable insights into the stability and dynamic behavior of these protein-ligand complexes during 100 ns MD simulations. The gene discussed is BUB1B; the disease is cervical carcinoma.