However it is interesting to note that in some of these infections with lower incidence in people with DS population, DYRK1A plays antiviral functions (e.g., HIV-1 and HPV), whereas in those that are more frequent or severe in this group (such as SARS-CoV-2), DYRK1A exerts proviral activities. This evidence concerns the gene DYRK1A and Dravet syndrome.