From PCa patient database (30), patients with TRIM28-high expression experienced significantly worse disease-free survival (Figure 1E and Supplemental Figure 1A; supplemental material available online with this article; https://doi.org/10.1172/JCI185119DS1) and showed a trend of worse overall survival (Supplemental Figure 1B). The gene discussed is TRIM28; the disease is posterior cortical atrophy.