In the vWAT progenitor cells (ASCs), there was a substantial increase in CCL2 (Figure 3F) and an increase in the expression of KDM6A (Figure 3H), as well as the acetylases CREBBP and EP300 (Figure 3J,K) in the patients with obesity. The gene discussed is CREBBP; the disease is obesity due to melanocortin 4 receptor deficiency.