Recent research suggests that remodelingof the actin cytoskeleton might enable cancer cell resistance to antitumorimmunity. Interestingly, several proteinslinked with invasion were significantly overexpressed in GB CL: MOES,EGFR, annexin A5 (ANXA5), vimentin (VIM), tenascin C (TENA), and cysteine-and glycine-rich protein 2 (CSRP2). Here, ANXA5 is linked to cancer.