Low HMGA2 expression was also linked to microsatellite instability (p = 0.0002) and BRAF mutations (p = 0.0018) as well as absence of RAS mutations (p < 0.0001) in colorectal cancer and HPV infection in squamous cell carcinomas (p < 0.0001, Supplementary Table 1). This evidence concerns the gene HMGA2 and squamous cell carcinoma.