The frequency of HMGA2 positivity was highest in cancers of the ovary and the endometrium (52.6–92.6%), thyroidal neoplasms (53.4–95%), salivary gland neoplasms (66.7–98%), and non-seminomatous testicular germ cell tumors (73.5–93.5%). This evidence concerns the gene HMGA2 and testicular germ cell tumor.