,36 Abnormal uterine contractions, aberrant angiogenesis, elevated levels of various angiogenic factors, α-smooth muscle actin, endothelial glycoproteins, S100A13, profilin, Matrix Metalloproteinases (MMPs), Nuclear Factor (NF)-κB, Tissue Factor (TF), and transforming growth factor-β1 are among the factors contributing to the development of anemia in AM women.37 This evidence concerns the gene S100A13 and anemia (phenotype).